Cell lines have become an extremely useful tool for studying protein interactions, gene activation and other biological processes because they represent a more natural biological
Author: Taylor Andrews
Western Blot Protocol
CONTENTS Introduction Lysate Preparation Sample Preparation SDS-PAGE Protein Transfer Immunoblotting Detection Buffers and Reagents INTRODUCTION Western blotting makes use of antibodies to determine particular person
General Sandwich ELISA Protocol
Introduction Sandwich ELISA (enzyme-linked immunosorbent assay) entails attachment of a seize antibody to a microplate. Then, samples containing unknown quantity of the goal protein or
Genetic and phenotypic landscape of the mitochondrial genome in the Japanese population.
The genetic landscape of mitochondrial DNA (mtDNA) has been elusive. By analyzing mtDNA using the whole genome sequence (WGS) of Japanese individuals (n = 1928), we identified
MSeqDR: A Centralized Knowledge Repository and Bioinformatics Web Resource to Facilitate Genomic Investigations in Mitochondrial Disease.
MSeqDR is the Mitochondrial Disease Sequence Data Resource, a centralized and complete genome and phenome bioinformatics useful resource constructed by the mitochondrial illness neighborhood to facilitate medical prognosis and analysis investigations
Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution.
The organism Caenorhabditis elegans is a performant mannequin system for finding out human organic processes and illnesses, however till now all phenome information are produced as population-averaged read-outs. Monitoring
Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies.
BACKGROUNDMitochondria play a crucial function in the cell and have DNA impartial of the nuclear genome. There is far proof that mitochondrial DNA (mtDNA) variation performs
P53 research
What is the role of the p53 gene? It does this remains unclear, although the p53 gene is vital for tumor suppression. Upon genotoxic or