Mitochondria Phenome Knowledgebase

Phenotypic Feature Hypertension finds 36 Gene-Feature associations that are associated with 28 Genes

Gene OMIM Disease Phenotypic Feature Phenotype Annotation Clinical Category PMIDs
ACADS 201470 Pregnancy-complications hypertension or hemolysis elevated liver enzymes and low platelets; HELLP syndrome genitourinary 14595061
ACADSB 610006 Pregnancy-complications hypertension; iron deficiency; low platelet counts genitourinary 12837870
CPOX 121300 Hypertension during attacks cardiovascular 7616659 9454777 9888388 11804210
CPT1A 255120 Hypertension arterial hypertension; pregnancy complication cardiovascular 10625081
CPT1A 255120 Pregnancy-complications hypertension or hemolysis elevated liver enzymes and low platelets; HELLP syndrome; acute fatty liver of pregnancy; AFLP syndrome; hyperemesis gravidarum; obstetric risks genitourinary 10625081
CPT2 255110 Hypertension cardiovascular 2748260
CYBA 233690 Hypertension arterial hypertension cardiovascular 9445163 10488959
CYP11B1 103900 Hypertension blood pressure elevated cardiovascular 1731223 7550315 7593610 10679515 12107222
CYP11B1 103900 Pregnancy-complications obstetric risks; preeclampsia; pregnancy aggravated hypertension; lower birth weights genitourinary 10679515
CYP11B1 202010 Headache-disorders related to hypertension neurologic 11095433
CYP11B1 202010 Hypertension arterial; deoxycorticosterone related cardiovascular 1430088 2022736 7488170 8506298 8768848 9302260 9435454 11095433 15755848 16030166
CYP11B1 202010 Vision-disorders blurred vision; vision loss; related to hypertension ophthalmologic 11095433
CYP11B2 103900 Hypertension blood pressure elevated; low renin hypertension cardiovascular 1731223 7550315 7593610 8954040 10679515 12107222
CYP11B2 103900 Pregnancy-complications obstetric risks; preeclampsia; pregnancy aggravated hypertension; lower birth weights genitourinary 10679515
DGUOK 251880 Liver-diseases hepatic failure; pseudoacinar transformation of hepatocytes; focal ground glass appearance; portal hypertension; hepatocellular insufficiency; glycogen depletion; cytolysis gastrointestinal 11687800 12205643 12210798 15639197 15883261 15887277 #15964659 16263314
DGUOK 251880 Pulmonary-edema pulmonary hypertension and edema; pulmonary arterial hypertension respiratory 15883261 16263314
DLAT 109720 Liver-diseases autoimmune; inflammation; hepatic failure; scarring; portal hypertension; nodular regenerative hyperplasia; liver damage; liver fibrosis gastrointestinal 3174635 7956610 8900092 10807520 #14708897 #16177252
DLAT 109720 Splenomegaly portal hypertension related; late stage miscellaneous 8900092 16177252
FH 605839 Hypertension hypertensive cardiovascular 15741255
GCK 125851 Hypertension arterial hypertension; uncommon finding cardiovascular 9049484
GK 307030 Hypertension several risk factors; GKD; smoking; fasting glucose levels elevated; hypertensive cardiovascular 11479736 16025401
HADHA 609015 Pregnancy-complications hypertension or hemolysis elevated liver enzymes and low platelets; HELLP syndrome; acute fatty liver of pregnancy; AFLP syndrome; hyperemesis gravidarum genitourinary 8865274 14630990
HADHA 609016 Pregnancy-complications hypertension or hemolysis elevated liver enzymes and low platelets; HELLP syndrome; acute fatty liver of pregnancy; AFLP syndrome; hyperemesis gravidarum; preeclampsia; premature birth; perinatal morbidity; perinatal mortality; maternal morbidity; maternal mortality; obstetric risks genitourinary 7846063 8094173 8736409 8931405 10352164 10518281 12413376 14605499
HADHB 609015 Pregnancy-complications hypertension or hemolysis elevated liver enzymes and low platelets; HELLP syndrome; hydrothoraces; hydrops generalisatus genitourinary 12548384 12754706
NDUFA12L 252010 Hypertension cardiovascular 16200211
OTC 311250 Pregnancy-complications hypertension or hemolysis elevated liver enzymes and low platelets; HELLP syndrome genitourinary 15578616
PEO1 607459 Hypertension arterial hypertension cardiovascular 15668446
PEO1 609286 Hypertension arterial hypertension; mild cardiovascular 12921794
POLG 157640 Hypertension history of hypertension cardiovascular 15534189
PPOX 176200 Hypertension hypertensive crisis cardiovascular 8673113 9763307 11804210 12357337 15643299
RMRP 250250 Esophageal-varices gastrointestinal bleeding; portal hypertension; esophagogastric varices gastrointestinal 11043437
SDHB 115310 Hypertension secondary hypertension; hypertensive crisis cardiovascular 9509062 11404820 12213855 14715873 15371856 15473885 16258955 16304664 16317055 16405730 16472267
SDHB 115310 Anxiety-disorders probably hypertension related; worsening anxiety; episodes; anxiety; nervousness; panic psychiatric 12213855 14715873 15473885 16472267
SDHD 168000 Hypertension hypertonia; blood pressure increased; hypertensive crisis cardiovascular 11156372 11605159 12782822 15365827 15762191 16317055
SLC25A4 609283 Hypertension angina pectoris; bypass surgery; heart attack cardiovascular 11756613
SOD1 105400 Hypertension paroxysmal hypertension; episodes; blood pressure fluctuations; due to sympathetic hyperactivity cardiovascular 9455983
TP53 202300 Hypertension cushing syndrome feature cardiovascular 11481490 11600572
UCP2 125853 Hypertension cardiovascular 15562023
WFS1 222300 Hypertension cardiovascular 12707373

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