Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles

Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles

Silver nanoparticles (AgNPs) are broadly used nanomaterials in each industrial and scientific biomedical purposes, however the molecular mechanisms underlying their exercise stay elusive. In this research we profiled proteomics and redox proteomics modifications induced by AgNPs in two lung most cancers cell traces: AgNPs delicate Calu-1 and AgNPs resistant NCI-H358. We present that AgNPs induce modifications in protein abundance and reversible oxidation in a time and cell line dependent method impacting essential mobile processes equivalent to protein translation and modification, lipid metabolism, bioenergetics and mitochondrial dynamics. Supporting confocal microscopy and transmission electron microscopy (TEM) knowledge additional emphasize mitochondria as a goal of AgNPs toxicity differentially impacting mitochondrial networks and morphology in Calu-1 and NCI-H358 lung cells. Proteomics knowledge can be found through ProteomeXchange with identifier PXD021493

Mitochondria gives mobile power via oxidative phosphorylation, and thus temperature-induced constraints on mitochondrial perform could also be essential to animal cardio scope and thermal tolerance. Here, we report the impact of temperature within the vary 5-30°C on respiration charges of remoted cardiac mitochondria from rainbow trout (Oncorhyncus mykiss) studied by high-resolution respirometry and spectrophotometric enzyme exercise assays. Arrhenius breakpoint temperature evaluation indicated that mitochondrial respiration charges below phosphorylating and totally uncoupled situations elevated exponentially up to 20°C, however stopped rising at larger temperatures. In distinction, respiration charges measured below non-phosphorylating leak situations continued to enhance up to 30°C.

The lower within the ratio between phosphorylating and uncoupled respiration at excessive temperature indicated that phosphorylation was step by step impaired with rising temperature, probably as a result of of the steadily rising proton leak throughout the membrane. In addition, we discovered that advanced I (NADH dehydrogenase) exercise decreased above 20°C, equally to mitochondrial respiration, and that advanced I used to be unstable within the presence of detergents, suggesting that it might be significantly delicate to modifications in its interplay with membrane phospholipids. In distinction, advanced II (succinate dehydrogenase) maintained exercise at temperatures above 20°C, though succinate oxidation was inadequate to compensate for the loss of advanced I exercise in intact mitochondria.

mTOR inhibition improves mitochondria perform/biogenesis and delays cardiovascular getting old in kidney transplant recipients with continual graft dysfunction

CVD stays the foremost trigger of mortality with graft functioning in Kidney transplant recipients (KTRs), with an estimated danger of CV occasions about 50-fold larger than within the common inhabitants. Many methods have been thought-about to scale back the CV danger such because the use of mTOR inhibitors. We consider whether or not continual mTOR inhibition would possibly affect CV getting old in KTRs finding out the molecular mechanisms concerned on this impact. We retrospectively analyzed 210 KTRs with steady graft perform on remedy with CNI and mycophenolic acid (Group A, 105 pts.), or with CNI and mTORi (Everolimus, Group B, 105 pts.).

The presence of mTOR inhibitor in immunosuppressive remedy was related to enhance serum ranges of Klotho with concomitant discount in FGF-23, with a major lower in left ventricular mass. In addition, KTRs with mTORi improved mitochondrial perform/biogenesis in PBMC with extra environment friendly oxidative phosphorylation, antioxidant capability and glutathione peroxidase exercise. Finally, group B KTRs introduced diminished ranges of inflammaging markers equivalent to diminished serum pentraxin-Three and p21ink expression in PBMC. In conclusion, we demonstrated that mTOR inhibition in immunosuppressive protocols prevents the prevalence and indicators of CV getting old in KTRs.

Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles

Tracking the formation and degradation of fatty-acid-accumulated mitochondria utilizing label-free chemical imaging

The mitochondrion is one of the important thing organelles for sustaining mobile homeostasis. External environmental stimuli and inner regulatory processes could alter the metabolism and features of mitochondria. To perceive these actions of mitochondria, it’s essential to probe the important thing metabolic molecules inside these organelles. In this research, we used label-free chemical imaging modalities together with coherent anti-Stokes Raman scattering and multiphoton-excited fluorescence to examine the mitochondrial actions in dwelling most cancers cells.

We discovered that hypothermia publicity tends to induce fatty-acid (FA) accumulation in some mitochondria of MIAPaCa-2 cells. Autofluorescence photographs present that the FA-accumulated mitochondria even have irregular metabolism of nicotinamide adenine dinucleotide hydrogen, possible induced by the dysfunction of the electron transport chain. We additionally discovered that when the cells had been re-warmed to physiological temperature after a interval of hypothermia, the FA-accumulated mitochondria modified their structural options.

Total Protein from Mouse Normal Tissue: Stomach

P1334248 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-82585 1 Kit Ask for price

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-96104 1 Kit Ask for price

cDNA from Mouse Normal Tissue: Stomach

C1334248 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Mouse Stomach OptiTDS: Tissue Dissociation System

4-28202 1 Kit Ask for price

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Medium

9-46104 5 x 100 ml Ask for price

Human Stomach Tissue Preparation Buffer: Normal Stomach Mucosa Epithelial Cells

9-80104 1 x 100 ml Ask for price

Rat Stomach Tissue Preparation Buffer: Normal Stomach Mucosa Epithelial Cells

9-80292 1 x 100 ml Ask for price

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Medium

9-25085 5 x 100 ml Ask for price

cDNA from Lupus: stomach

C1236248Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Stomach Tumor lysate

HTL-1340 1 mg
EUR 773

Human Stomach Tissue Lysate

30R-AS039 150 ug
EUR 219
Description: Fresh tissue lysate isolated from human stomach

Genomic DNA from Mouse Normal Tissue: Stomach

D1334248 100 ug
EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Mouse Normal Tissue: Stomach

R1334248-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Immortalized Mouse Stomach Epithelial Cells-Conditionally (ImSt)

T0569 1x106 cells / 1.0 ml Ask for price

Total Protein from Human Tumor Tissue: Stomach

P1235248 1 mg
EUR 320
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Diabetic Tissue: Stomach

P1236248Dia 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Tumor Tissue: Stomach

P3235248 0.1 mg
EUR 408
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rat Stomach Whole tissue lysate

RAL-1475 1 mg
EUR 524

Total RNA from Lupus: Stomach

R1236248Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Mouse Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-33088 1 Set Ask for price

Total Protein from Human Adult Normal Tissue: Stomach

P1234248 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Stomach

P3234248 0.1 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

cDNA from Human Tumor Tissue: Stomach

C1235248 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Stomach

C1236248Dia 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Stomach

C1434248 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Stomach

C1734248 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Stomach OptiTDS: Tissue Dissociation System

4-28292 1 Kit Ask for price

Human Stomach OptiTDS: Tissue Dissociation System

4-28104 1 Kit Ask for price

Human Cancer PrimaCell16: Stomach Tumor Cells

2-96039 1 Kit Ask for price

Total RNA from Diabetic Disease: Stomach

R1236248Dia-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Frozen Tissue Section - Human Tumor: Stomach

T1235248 5 slides
EUR 338
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Epithelial Dissociation System 10 (Stomach epithelial), Mouse and Rat

4-20260 ea Ask for price

Human, Mouse, Rat - Stomach Tissue Array (5 slides/pk)

TAS-1013 1 pk
EUR 286

Total Protein from Human Adult Normal Tissue: Stomach: Cardia

P1234250 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Adult Normal Tissue: Stomach: Corpus

P1234251 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Adult Normal Tissue: Stomach: Fundus

P1234252 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Adult Normal Tissue: Stomach: Pylorus

P1234253 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Stomach: Cardia

P3234250 0.1 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Stomach: Corpus

P3234251 0.1 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Stomach: Fundus

P3234252 0.1 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Stomach: Pylorus

P3234253 0.1 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Mouse Stomach FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

7-15181 1 Kit Ask for price

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-47104 1 Set Ask for price

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-26085 1 Set Ask for price

cDNA from Human Adult Normal Tissue: Stomach

C1234248 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Stomach

C1534248 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Cynomolgus) Normal Tissue: Stomach

C1534248-Cy 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Adult Stomach (Normal) Whole tissue lysate

HAL-1319 1 mg
EUR 524

Genomic DNA from Rat Normal Tissue: Stomach

D1434248 100 ug
EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

FFPE Genomic DNA - Human Tumor Tissue: Stomach

D2235248 2 ug
EUR 821
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

96 Well Stomach Tumor Genomic DNA Plate

D8235248-1 1 plate
EUR 316

Monkey (Rhesus) Normal Stomach Whole tissue lysate

MRL-1321 1 mg
EUR 524

Pepsin (3000 U/mg), Porcine Stomach Mucosa

PEP15-01 1 g
EUR 141

Monkey (Cyno.) Normal Stomach Whole tissue lysate

MCL-1210 1 mg
EUR 524

Total RNA from Human Tumor Tissue: Stomach

R1235248-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Stomach

R1434248-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Frozen Tissue Section - Human Adult Normal: Stomach

T1234248 5 slides
EUR 349
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Section - Human Diabetic Tissue: Stomach

T1236248Dia 5 slides
EUR 465
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Adult Normal: Stomach

T2234248 5 slides
EUR 211
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

CancerSeq? Plus Paraffin Tissue Tumor Sections: Stomach

T2235248-SC 5 curls
EUR 932
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Diabetic Tissue: Stomach

T2236248Dia 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Cancer of the stomach, 102 cases (1.5mm)

STC1021 1
EUR 250
Description: Stomach cancer tissue array, 102 cases of normal/benign (5 cases) and cancer (97 cases with grading and TNM staging data) tissues

Cancer of the stomach, 228 cases (1.1mm)

STC2281 1
EUR 460
Description: Stomach cancer tissue array containing 8 cases of normal/benign conditions and 220 cases of cancers with grading and TNM staging data.

Mouse Ferritin, Mitochondrial (FTMT) Protein

20-abx066552
  • EUR 676.00
  • EUR 272.00
  • EUR 2068.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Mitochondrial Protein

abx061499-200ug 200 ug
EUR 648
  • Shipped within 5-10 working days.

cDNA from Human Adult Normal Tissue: Stomach: Cardia

C1234250-10 10 reactions
EUR 231
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Corpus

C1234251-10 10 reactions
EUR 231
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Fundus

C1234252-10 10 reactions
EUR 231
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Pylorus

C1234253-10 10 reactions
EUR 231
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Stomach: Cardia

C1534250 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Stomach: Corpus

C1534251 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Stomach: Fundus

C1534252 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Stomach: Pylorus

C1534253 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Stomach Tissue Slide (Normal) (5 slides/pk)

HTS-10801 1 pk
EUR 286

Human Stomach Tissue Slide (Benign) (5 slides/pk)

HTS-10803 1 pk
EUR 286

Human Stomach Tissue Slide (Carcinoma) (5 slides/pk)

HTS-10807 1 pk
EUR 286

Human Stomach Tissue Slide (Adenocarcinoma) (5 slides/pk)

HTS-10809 1 pk
EUR 286

Human Stomach Tissue Slide (Carcinoma) (5 slides/pk)

HTS-10814 1 pk
EUR 286

Human Stomach Tissue Slide (Abnormal) (5 slides/pk)

HTS-10826 1 pk
EUR 286

Human Stomach Tissue Slide (Tumor) (5 slides/pk)

HTS-10827 1 pk
EUR 286

Human Cancer PrimaCell16: Stomach Tumor Cells Growth Medium

9-46039 5 x 100 ml Ask for price

Total RNA from Human Adult Normal Tissue: Stomach

R1234248-50 50 ug
EUR 178
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Monkey (Rhesus) Normal Tissue: Stomach

R1534248-50 50 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Monkey (Cynomolgus) Normal Tissue: Stomach

R1534248-Cy 50 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Common diseases of the stomach, 24 cases (2mm)

STD481 1
EUR 221
Description: Stomach disease tissue array, 48 cores, 24 cases of normal, inflammatory and neoplastic conditions of the stomach in duplicates

Mouse Mitochondrial Ribosomal Protein L1 (MRPL1) Protein

20-abx650082
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Mitochondrial Ribosomal Protein L2 (MRPL2) Protein

20-abx650639
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Acyl Carrier Protein, Mitochondrial (ACP) Protein

20-abx065145
  • EUR 732.00
  • EUR 286.00
  • EUR 2291.00
  • EUR 871.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Uncoupling Protein 1, Mitochondrial (UCP1) Protein

20-abx069600
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Uncoupling Protein 2, Mitochondrial (UCP2) Protein

20-abx069604
  • EUR 746.00
  • EUR 300.00
  • EUR 2346.00
  • EUR 899.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Mouse Proline Dehydrogenase, Mitochondrial (PRODH) Protein

20-abx650164
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Topoisomerase I, Mitochondrial (TOP1MT) Protein

20-abx650477
  • EUR 732.00
  • EUR 286.00
  • EUR 2263.00
  • EUR 871.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse 5'-Nucleotidase, Mitochondrial (NT5M) Protein

20-abx650541
  • EUR 815.00
  • EUR 314.00
  • EUR 2611.00
  • EUR 982.00
  • EUR 578.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Aldehyde Dehydrogenase, Mitochondrial (ALDM) Protein

20-abx652448
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Mouse Folylpolyglutamate Synthase, Mitochondrial (FPGS) Protein

20-abx168991
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Calcium uniporter protein, mitochondrial (Mcu)

1-CSB-CF668882MO
  • EUR 1286.00
  • EUR 560.00
  • EUR 816.00
  • 1MG
  • 200ug
  • 500ug
  • MW: 37.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Calcium uniporter protein, mitochondrial(Mcu) expressed in in vitro E.coli expression system

Stomach Tumor Tissue Array - Duplicated 70 cases covering all the common types of stomach cancer and 5 cases of normal

Z7020046 5 slides
EUR 1381
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Stomach Tumor Tissue Array - Duplicated 36 cases covering all the common types of stomach cancer and 12 cases of normal

Z7020048 5 slides
EUR 1381
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Bovine Lysozyme C, non- stomach isozyme, LYS ELISA KIT

ELI-23778b 96 Tests
EUR 928

Human Stomach Tissue Slide (Mucinous adenocarcinoma) (5 slides/pk)

HTS-10810 1 pk
EUR 286

Human Cancer Tissue Preparation Buffer 16: Stomach Tumor Cells

9-80039 1 x 100 ml Ask for price

Genomic DNA from Lupus: Stomach, from a single donor

D1236248Lup 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Human Adult Normal Tissue: Stomach: Cardia

R1234250-10 10 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Human Adult Normal Tissue: Stomach: Corpus

R1234251-10 10 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Human Adult Normal Tissue: Stomach: Fundus

R1234252-10 10 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Human Adult Normal Tissue: Stomach: Pylorus

R1234253-10 10 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Paraffin Tissue Section - Human Stomach Tumor: Adenocarcinoma Poorly Differentiated

T2235248-1 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Stomach Tumor: Squamous Cell Carcinoma

T2235248-10 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Stomach Tumor: Adenocarcinoma, Moderately Differentiated

T2235248-2 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Stomach Tumor: Adenocarcinoma, Well Differentiated

T2235248-3 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Cancer of the stomach, 75 cases (1.1mm), set 1

STC1501 1
EUR 250
Description: Stomach cancer tissue array, set 1, non-overlapping with STC1502 or STC1503, 150 cores from normal/benign (5 cases) and cancer (70 cases with grading and TNM staging data) tissues in duplicates

Cancer of the stomach, 75 cases (1.1mm), set 2

STC1502 1
EUR 250
Description: Stomach cancer tissue array, set 2, non-overlapping with STC1501 or STC1503, 150 cores from normal/benign (5 cases) and cancer (70 cases with grading and TNM staging data) tissues in duplicates

Cancer of the stomach, 75 cases (1.1mm), set 3

STC1503 1
EUR 250
Description: Stomach cancer tissue array, set 3, non-overlapping with STC1501 or STC1502, 150 cores from normal/benign (5 cases) and cancer (70 cases with grading and TNM staging data) tissues in duplicates

Mouse Frataxin, mitochondrial (Fxn)

1-CSB-YP009086MO
  • EUR 504.00
  • EUR 265.00
  • EUR 1832.00
  • EUR 763.00
  • EUR 1216.00
  • EUR 334.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 16.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Frataxin, mitochondrial(Fxn) expressed in Yeast

Mouse Frataxin, mitochondrial (Fxn)

1-CSB-EP009086MO
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 30.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Frataxin, mitochondrial(Fxn) expressed in E.coli

Mouse Frataxin, mitochondrial (Fxn)

1-CSB-EP009086MOa0
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 19.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Frataxin,mitochondrial(Fxn) expressed in E.coli

Mouse Mitochondrial Tumor Suppressor 1 (MTUS1) Protein

20-abx650090
  • EUR 676.00
  • EUR 286.00
  • EUR 2082.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Mitochondrial Methionyl tRNA Formyltransferase (MTFMT) Protein

20-abx650741
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Creatine Kinase, Mitochondrial 1A (CKMT1A) Protein

20-abx653063
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Mouse Mitochondrial Ribosomal Protein L17 ELISA kit

E03M0227-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Mitochondrial Ribosomal Protein L17 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mitochondrial Ribosomal Protein L17 ELISA kit

E03M0227-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Mitochondrial Ribosomal Protein L17 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mitochondrial Ribosomal Protein L17 ELISA kit

E03M0227-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Mitochondrial Ribosomal Protein L17 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Protein preY, mitochondrial, Prey ELISA KIT

ELI-15662m 96 Tests
EUR 865

Mouse Twinkle protein, mitochondrial, Peo1 ELISA KIT

ELI-16041m 96 Tests
EUR 865

Mouse Protein ETHE1, mitochondrial, Ethe1 ELISA KIT

ELI-47260m 96 Tests
EUR 865

Mouse Carbonic Anhydrase VB, Mitochondrial (CA5B) Protein

20-abx065699
  • EUR 718.00
  • EUR 286.00
  • EUR 2221.00
  • EUR 857.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Mouse Superoxide Dismutase 2, Mitochondrial (SOD2) Protein

20-abx069198
  • EUR 495.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 578.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Mouse Transcription Factor A, Mitochondrial (TFAM) Protein

20-abx069400
  • EUR 815.00
  • EUR 314.00
  • EUR 2569.00
  • EUR 968.00
  • EUR 565.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Protein Dihydroorotate dehydrogenase (quinone), mitochondrial (Dhodh)

1-CSB-CF006852MO
  • EUR 1333.00
  • EUR 607.00
  • EUR 863.00
  • 1MG
  • 200ug
  • 500ug
  • MW: 44.2 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Protein Dihydroorotate dehydrogenase (quinone), mitochondrial(Dhodh) expressed in in vitro E.coli expression system

Stomach Tumor Tissue Array - Duplicated 70 cases covering all the common types of stomach cancer and 5 cases of normal a

Z7020045 5 slides
EUR 1381
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Human Stomach FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

7-15093 1 Kit Ask for price

Rat Stomach FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

7-15262 1 Kit Ask for price

Genomic DNA - Human Diabetic Tissue: Stomach, from a single donor

D1236248Dia 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Cancer of the stomach paired with metastasis, 48 cases (1.5mm)

STM961 1
EUR 361
Description: Stomach cancer tissue array containing 48 cases of paired primary and metastatic tumors (in lymph nodes and other organs) from the same patients.

Paraffin Tissue Section - Human Stomach Tumor: Signet-Ring Cell Carcinoma

T2235248-9 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Matching Pair - Total Protein from Human Primary Tumor and Normal Tissue (PP): Stomach

P8235248-PP 0.2 mg x2
EUR 639
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Mitochondrial Antigen, M2 Protein

abx069884-1000Units 1000 Units
EUR 1435
  • Shipped within 5-10 working days.

Mitochondrial Protein IP Kit

K285-50
EUR 490

Mitochondrial Ribosomal Protein L1 Protein

20-abx261932
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.

Mouse Mitochondrial uncoupling protein 2 (UCP2) ELISA Kit

abx519287-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

Mouse Uncoupling Protein 2, Mitochondrial (UCP2) CLIA Kit

20-abx496461
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Mouse Uncoupling Protein 2, Mitochondrial (UCP2) ELISA Kit

20-abx585023
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

To the perfect of our information, that is the primary time that FA accumulation in mitochondria was noticed in dwell cells. Our analysis additionally demonstrates that multimodal label-free chemical imaging is a pretty instrument to uncover irregular features of mitochondria on the single-organelle stage and can be utilized to quantify the dynamic modifications of these organelles below perturbative situations. Brown and beige adipocytes are mitochondria-enriched cells succesful of dissipating power within the kind of warmth. These thermogenic fats cells had been initially thought-about to perform solely in warmth era via the motion of the mitochondrial protein uncoupling protein 1 (UCP1). In latest years, vital advances have been made in our understanding of the ontogeny, bioenergetics and physiological features of thermogenic fats.

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