The role of melatonin in sarcopenia: Advances and application prospects
Sarcopenia is an age-related illness that has progressively develop into a severe well being downside for aged people. It not solely significantly will increase the
Freeze-thawing impairs the motility, plasma membrane integrity and mitochondria function of boar spermatozoa through generating excessive ROS
Cryopreservation is an environment friendly approach to retailer spermatozoa and is intently related to the high quality of sperm after the freeze-thaw course of. During
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis
Human hexokinase 2 is a vital regulator of glycolysis that {couples} metabolic and proliferative actions in cancer cells. The binding of hexokinase 2 to the
Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells
Vaginal candidiasis is a particularly frequent illness predominantly attributable to 4 phylogenetically numerous species: Candida albicans; Candida glabrata; Candida parapsilosis; and Candida tropicalis. Using a
Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles
Silver nanoparticles (AgNPs) are broadly used nanomaterials in each industrial and scientific biomedical purposes, however the molecular mechanisms underlying their exercise stay elusive. In this
Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency
Long-chain fatty acid oxidation is steadily impaired in major and systemic metabolic ailments affecting the guts, thus therapeutically growing reliance on usually minor energetic substrates,
Neurodegenerative Diseases
Alzheimer’s Disease Common or sporadic Alzheimer’s disease (AD) occurs late in life, usually after the age of 70, and accounts for the vast majority of
Rent cell lines at BPS Bioscience
Cell lines have become an extremely useful tool for studying protein interactions, gene activation and other biological processes because they represent a more natural biological
Western Blot Protocol
CONTENTS Introduction Lysate Preparation Sample Preparation SDS-PAGE Protein Transfer Immunoblotting Detection Buffers and Reagents INTRODUCTION Western blotting makes use of antibodies to determine particular person
General Sandwich ELISA Protocol
Introduction Sandwich ELISA (enzyme-linked immunosorbent assay) entails attachment of a seize antibody to a microplate. Then, samples containing unknown quantity of the goal protein or